The rationale for targeted therapies in medulloblastoma
نویسندگان
چکیده
منابع مشابه
The rationale for targeted therapies in medulloblastoma.
Medulloblastoma (MB) is the most frequent malignant brain tumor in children. Patients with MB who are classified as having high-risk disease or those with recurrent disease respond poorly to current therapies and have an increased risk of MB-related mortality. Preclinical studies and molecular profiling of MB tumors have revealed upregulation or activation of several key signaling pathways such...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2013
ISSN: 1523-5866,1522-8517
DOI: 10.1093/neuonc/not147